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Activyl Flea Treatment For Cats

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What Pet Owners Need To Know

Activyl Flea Treatment for Cats

If you have questions about the Seresto Flea and Tick Collar, or any other flea-control product, speak to your veterinarian for advice. Regardless of what type of flea-control product you choose for your cat, the EPA urges pet owners to read the entire label before using the product, follow all directions carefully, and monitor your pet after treatment.

There are also reports of counterfeit Seresto collars on the market, particularly through online retailers. Petco and Petsmart, major suppliers of pet products, told us that they purchase Seresto collars directly from the manufacturer, Elanco. It’s important to purchase from a reputable website, brick-and-mortar store with a guarantee program, or for the most assurance, directly from your veterinarian. Before placing a Seresto collar on your pet, we also recommend that pet owners call Elanco product support to verify the authenticity of the product’s serial number.

If you suspect that your pet is having an adverse reaction to a flea collar, immediately remove the collar and call your veterinarian. Carroll also advises pet owners to contact theNational Pesticide Information Center, which is an EPA information-sharing partner with staff who are specially trained to respond to pesticide exposure incidents, as well as to report adverse reactions from flea collars and topical treatments on the EPA’s website.

Avoid Natural Flea Control Products

If you’re considering using natural flea control products that contain essential oils, exercise caution. Some essential oils can be toxic to cats.

All three veterinarians we consulted do not recommend natural products, which do not work nearly as well as veterinarian-recommended topical and oral flea control products. “They are just not proven to be really effective,” Bourgeois said. “My biggest concern with natural products is, even if they’re safe, if they’re not effective, that’s not helping our pets. I get more concerned about the secondary ramifications for the pet if we’re using something that hasn’t been proven to be effective, versus products that have been proven to be effective and well tolerated.”

What Makes Activyl Flea Treatment Different

Activyl contains indoxacarb, which was specifically developed to overcome insect resistance in crop protection. Indoxacarb is a pro-insecticidal compound that requires enzymatic activation in the flea where it is converted into its highly potent insecticidal form. Activyl is metabolized differently in insects than in mammals. Unlike insects, mammals mostly metabolize indoxacarb into nontoxic metabolites.

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What Are The Side Effects Of Activyl

A brief period of hypersalivation has been reported after treatment with Activyl for Dogs. Less common adverse reactions include squinting, head shaking, and scratching or rubbing the site of product application.

The most common reported side effects after treatment with Activyl Tick Plus are transitory erythema , hair loss or itching. Less common reactions include gastrointestinal sing, lethargy and diarrhea.

Adverse reactions reported for cats treated with Activyl for Cats include temporary hypersalivation and irritation. Less common adverse reactions include squinting, head shaking, and scratching or rubbing the site of product application.

How Do You Use Activyl

Merck Activyl Topical Flea Treatment for Large Cats Over 9lbs 3 Month ...

Open the pouch and remove the tube. Hold the tube at the crimped end with the cap in an upright position . The cap should be rotated clockwise or counter clockwise one full turn. The cap is designed to stay on the tube for dosing and should not be removed. The tube is open and ready for application when a click is heard or felt. This indicates that the seal is broken and product can be applied to the cat.

The cat should be standing or lying with its back horizontal during application. Part the fur at the administration site. Place the tube tip vertically against the skin at the base of the skull of the cat.

Treatment at the base of the skull will minimize the opportunity for the cat to lick the product.

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Activyl Kills 90% Of Fleas Within 24 Hours

Activyl kills fleas at all stages of their life cycle from immature to adult and reduces the flea population in the home for up to 4 weeks. It affects more than just the adult fleas, inhibiting the entire flea life cycle from egg to adult, and effectively eliminates the problem completely. The product is effective at preventing infestation in the household, leaving the home flea-free within 3 months.

Activyl is waterproof and begins working immediately, killing over 90% of adult fleas within 12 hours. Moreover, it inhibits the development of flea eggs and larvae, which prevents their reinfestation in the environment. Most pets are safe to use, although Activyl may cause excessive itchiness or irritation on sensitive skin. Although Activyl is safe for use on most dogs and puppies, long haired pets should be treated differently.

Activyl Spot-On treats fleas in dogs and cats. It uses the active metabolite indoxacarb to impair flea nerve cell membranes. By blocking sodium current amplitude, it prevents developing fleas from biting your pets and breaks their life cycle. The Activyl Spot-On is effective against adult fleas, eggs and larvae, and also provides sustained control over new flea infestations for up to 4 weeks.

What About Flea Sprays

Flea sprays are cheaper than their topical or oral counterparts. But many products need weekly applications, so in the long run they arent as cost-effective or convenient as a monthly topical or chew. Since these treatments kill on contact, you also generally need to spray down your entire pet, which takes a lot more work than a couple of drops on the scruff of the neck.

Some treatments, like Advantage Treatment Spray for Dogs, direct owners to rub the spray around the pets eyes, nose, and mouth, and they can cause adverse reactions if ingested. Others, like Vets Best Flea & Tick Home Spray for Cats, contain essential oils that are toxic to cats. Some sprays also contain alcoholwhich sometimes isnt disclosedwarned the ASPCAs Wismer. If a pet is soaked with one of these products, they can actually become intoxicated, and this requires immediate veterinary care, she said.

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Activyl Feline Topical Over 9lbs Only


  • Please note: Activyl Feline 2-9# is no longer available. Please see Cheristin by Elanco for cats as an alternative for a non-prescription flea control product.
  • Minimum Age: 8 weeks
  • Apply topically to the back of the neck
  • Effective flea control for 1 month
  • Activyl also kills flea larva and prevents flea eggs from hatching.

More Questions About Activyl

Activyl Cats Flea Treatment

How soon can I touch my cat after applying Activyl?

Let the application dry before touching your cat.

How long does it start to work after application?

Kills 100% of fleas within 8 hours of application.

Can my cat get wet/ how long does the cat need to stay dry?

While the product should be dry within 24 hours. Keep in mind that more frequent bathing may keep the product from working for the full 30 days.

My pet is on medication for another condition right now. Is it still safe to give Activyl?

Studies with Activyl have shown no interactions with routinely used veterinary medicinal products. However, it is always best to discuss all of your pets treatments with your veterinarian as they are your pets health care expert.

Does Activyl smell?

Labeling states there is no odor to this product.

Are there potential side effects of Activyl? What happens if my cat licks Activyl?

In cats, accidental ingestion may cause intermittent salivation, licking of the face, shaking of the head, and squinting.

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Why You Should Trust Me

As Wirecutters pets writer, Ive covered everything from essential oil myths to how to get rid of fleas. Im also a lifelong pet owner and a shelter volunteer with over a decade of experience whos dealt with her share of pets with fleas, ticks, and other pests.

For this guide, I spoke with six professionals, from veterinarians to pesticide experts, about how to select the best flea and tick treatment for your pet. I spoke with Jennifer Gervais, a pesticide specialist at the National Pesticide Information Center, and Ken Labbe, a spokesperson for the U.S. Environmental Protection Agency about pesticide regulation. I consulted Dr. Douglas Kratt, president of the American Veterinary Medical Association, about how to select the appropriate medication for your pet. I asked Dr. Tierra Price, a spay-neuter surgeon and founder of the BlackDVM Network, and Dr. Jennifer Welser, chief medical officer at , about their favorite flea and tick medications. And I discussed product safety with Dr. Tina Wismer, senior director of the ASPCA Animal Poison Control Center.

Activyl Flea Treatment For Cats

Activyl Flea Treatment for Cats is the only spot-on treatment for cats that kills 98% of fleas in just 6 hours.

activyls active ingredient, indoxacarb, is a new type of insecticide called a co-metabolite that gets inside the flea to target its nervous system. this means it can kill fleas before they have a chance to lay eggs and ensures all your cats bedding, carpets, and soft furnishings remain protected too.

activyl also spreads rapidly through your cats blood, killing newly arriving fleas within 2 hours*, breaking the flea life cycle at every stage to ensure complete protection against further attacks. *based on lab studies with healthy adult cats under veterinary supervision.

Note: Activyl should not be used on sick or convalescing cats

actavyl is a topical treatment for controlling fleas in cats. indoxacarb, the active ingredient in activyl, spreads through your cats blood to kill any newly arriving fleas within 2 hours*. activatings unique formula ensures all your cats bedding, carpets, and soft furnishings remain protected too. note: activyl should not be used on sick or convalescing cats.

*based on lab studies with healthy adult cats under veterinary supervision.

Note: Activyl should not be used on sick or convalescing cats.

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How Often Is Activyl Applied

To break the flea life cycle Activyl is applied directly to the skin every 4 weeks. By doing this Activyl ensures that fleas that jump onto your pet will stop feeding, become paralysed and die. In addition Activyl controls the immature stages of the flea’s life cycle in the environment and so prevents reinfestation. Studies have shown that Activyl is still 100% effective at 30 days after application.

Activyl Kills Fleas Within 8 Hours

ACTIVYL Flea Treatment for Cats &  Kittens, 2

In the past, the best option to treat fleas on cats was using a topical solution, but the time is now right to make the switch. Activyl kills fleas within eight hours and can paralyze adult fleas. It also prevents flea eggs from developing into larvae and biting adults, and provides sustained control for at least four weeks. For more information, visit the Activyl website.

There are several effective topical treatments for fleas, but its important to know your pets needs and the environment in which you live. Many veterinarians recommend using a combination of topical and oral treatments to control fleas. Activyl kills fleas within 8 hours and is effective against ticks and adult fleas. It can be applied to cats and dogs, and lasts for up to six weeks.

Activyl works by moving through the oily coating on the cats skin. Its important to choose the right product for the amount of weight your cat weighs. Once on the cat, Activyl begins killing fleas within eight hours, and the majority of them are dead by the end of the day. The product has an effective kill rate of up to 90%. However, the product should only be applied to your pets skin once every month.

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Dosage & Safety Information

Activyl for cats should be administered topically as a single dose every 4 weeks.

Treatment with Activyl for cats may begin at any time of the year and can continue year round without interruption.

What happens if I miss a dose?

Give the dose when you remember and resume the normal application schedule of one application every 4 weeks.

Can it be used on kittens?

It is safe to use in kittens 2 months of age and older, and weighing 2.0 lbs or greater.

Can it be used on pregnant cats?

No, the safety of Activyl has not been established in breeding, pregnant and lactating cats.

What Are The Health Risks To A Cat

Fleas are more than just a nuisance. These parasites can pose a threat to your cat’s health. A severe flea infestation can seriously damage a cat’s skin, induce an allergic reaction, or cause them to become anemic from blood loss. Fleas are also responsible for cats contracting parasites like tapeworms and may transmit diseases.

“Fleas can pass on diseases to cats, which can then be passed on to people,” Jeffer said. “The most common one that we see is cat scratch fever , which can cause all kinds of issues in people, but in cats, it can make them very sick.”

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Can A Flea Collar Harm Your Cat

The safety of flea and tick collars has been in the news lately, specifically the bestselling Seresto flea and tick collar, which was developed by Bayer and is now sold by Elanco Animal Health. On March 2, 2021, USA Today and the Midwest Center for Investigative Reporting published a report maintaining that the Seresto collar has been linked to thousands of adverse incidents, including pet deaths and incidents of harm to humans.

The Center for Biological Diversity filed a legal petition in April urging the U.S. Environmental Protection Agency to cancel the registration of the Seresto flea and tick collar. A week later, the American Veterinary Medical Association published an article addressing the controversy surrounding the Seresto collar. According to the AVMA, Seresto’s “manufacturer has defended the collars as safe and effective, and veterinary experts say they have seen no cause for alarm.”

Additionally, Elanco published a statement on its website calling the media coverage “misleading” and stating that the company stands by the product. “All data and scientific evaluation used during the product registration process and through Elanco’s robust pharmacovigilance review supports the product’s safety profile and efficacy,” the statement reads.

Some Flea Products Are Dangerous To Cats

Activyl® Flea Treatment for dogs & puppies

Products labeled for use in dogs only should never be used on a cat. Some ingredients that are well-tolerated by dogs can be toxic to cats. “Anything with a permethrin, also known as pyrethrin, should never be used on a cat,” Sawyer said. ” are very sensitive to pyrethrins and can have significant neurologic side effects, even death. Never use a product labeled for a dog on a cat as it may have pyrethrins in it even if not exclusively mentioned on the label.”

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A Unique Mode Of Action

This enzymatic cleavage occurs in insects but not mammals. Mammals metabolize indoxacarb differently, mostly to non-toxic metabolites. In addition, compared to insects, mammalian sodium channels are significantly less sensitive to bioactivated indoxacarb.

Activyl provides selective toxicity through:

  • High rate of biological activation in susceptible insects
  • Differential sensitivity of sodium ion channels between insects and mammals: significantly lower concentrations are effective in insects.3
  • Alternative metabolic pathways in mammals convert indoxacarb mainly to non-toxic metabolites.3, 4
  • Relatively minor biological activation in mammals. 3, 4

Indoxacarb produces its potent effects at a unique binding site in voltage-gated sodium ion channels of the nervous system of susceptible insects.4 This effect differs strikingly from those reported for other insecticides such as pyrethroids, also known to affect the voltage-dependant sodium channels, but at a different site.1, 2, 4

The active metabolite of indoxacarb induces irreversible hyperpolarization of insect nerve cell membranes. It blocks the sodium current amplitude in the neuron differently than the pyrethroids. This results in impaired insect nerve function, feeding cessation, paralysis and death of susceptible insects.

Activyl For Dogs And Puppies

Activyl is a monthly spot-on flea control for dogs. The active ingredient in Activyl is indoxacarb, which works by bioactivation enzymes inside the flea activate indoxacarb and release its full flea-killing power. There is no known flea resistance to indoxacarb. Activyl stops fleas from feeding, kills all flea stages , and inhibits flea development in the environment.

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Activyl Breaks The Flea Life Cycle

Unlike some flea treatments, Breaking the flea life cycle is important, so your pet is not re-infested by new fleas developing from flea eggs and larvae in your own home environment.

Activyl for Dogs is the flea treatment just for dogs and Activyl for Cats is the flea treatment just for cats.Both products kill adult fleas and also break the flea life cycle, so you’re much more likely to solve your pet’s problem for good.

Activyl Kills 90% Of Fleas Within 48 Hours

Activyl® Topical for Cats &  Kittens

Activyl is a topical flea remedy for dogs. It contains an active ingredient called indoxacarb, which reacts with enzymes in fleas. As soon as it comes into contact with the dogs skin, Activyl paralyzes the fleas, preventing them from feeding and biting. This product kills fleas for up to four weeks, making it an excellent flea treatment.

This topical treatment is safe and effective, killing over 90% of the adult fleas within 48 hours. Activyl comes in 4 different sizes to suit every dog, including Toy dogs and small dogs. It is applied to the dog in three spots on its back. In eight hours, the fleas will have died off. Activyl is available in a monthly dose, which means that one dose will last your dog for one month.

Activyl is an effective flea treatment for cats and dogs. The treatment works within 48 hours, and it is safe for cats and dogs over 2 kg. The treatment is also effective against adult fleas and their eggs. The treatment is recommended by veterinarians. It kills fleas on dogs and cats and will protect them from recurrence for up to 8 months.

While fleas can live and reproduce in your pets environment for months, it can lay dormant during winter. These tiny parasites lay dormant until they are right for their egg-laying stage. Once they hatch, they will feed on your pet, multiply, and reproduce. Therefore, the best way to combat fleas is to use a product that targets all stages of their life cycle.

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